PDE6D Antibody
Code | Size | Price |
---|
PSI-59-162-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta, Protein p17, PDE6D, PDED
Application Note:
For WB starting dilution is: 1:1000
Background:
Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation.
Background References:
- Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
- Wilson, S.J., et al. J. Biol. Chem. 281(17):11780-11786(2006)
- Stelzl, U., et al. Cell 122(6):957-968(2005)
- Hanzal-Bayer, M., et al. EMBO J. 21(9):2095-2106(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PDE6D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the Central region of human PDE6D.
NCBI Gene ID #:
5147
NCBI Official Name:
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
NCBI Official Symbol:
PDE6D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
O43924
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O43924
User NOte:
Optimal dilutions for each application to be determined by the researcher.