CYLN2 Antibody
| Code | Size | Price |
|---|
| PSI-59-428-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CAP-Gly domain-containing linker protein 2, Cytoplasmic linker protein 115, CLIP-115, Cytoplasmic linker protein 2, Williams-Beuren syndrome chromosomal region 3 protein, Williams-Beuren syndrome chromosomal region 4 protein, CLIP2, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the family of
cytoplasmic linker proteins, which have been proposed to mediate
the interaction between specific membranous organelles and
microtubules. This protein was found to associate with both
microtubules and an organelle called the dendritic lamellar body.
This gene is hemizygously deleted in Williams syndrome, a
multisystem developmental disorder caused by the deletion of
contiguous genes at 7q11.23. Alternative splicing of this gene
generates 2 transcript variants.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Cheng, J., et al. Science 308(5725):1149-1154(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This CYLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-940 amino acids from the C-terminal region of human CYLN2.
NCBI Gene ID #:
7461
NCBI Official Name:
CAP-Gly domain-containing linker protein 2
NCBI Official Symbol:
CLIP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
116 kDa
Protein Accession #:
Q9UDT6
Protein GI Number:
74753268
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9UDT6
User NOte:
Optimal dilutions for each application to be determined by the researcher.