CTNND2 Antibody
| Code | Size | Price |
|---|
| PSI-56-497-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes an adhesive junction associated protein
of the armadillo/beta-catenin superfamily and is implicated in
brain and eye development and cancer formation. The protein encoded
by this gene promotes the disruption of E-cadherin based adherens
junction to favor cell spreading upon stimulation by hepatocyte
growth factor. This gene is overexpressed in prostate
adenocarcinomas and is associated with decreased expression of
tumor suppressor E-cadherin in this tissue. This gene resides in a
region of the short arm of chromosome 5 that is deleted in Cri du
Chat syndrome.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Zhang, J., et al. Exp. Cell Res. 316(6):1070-1081(2010)
- Yang, I., et al. Mol. Cells 29(3):233-237(2010)
- Stenzel, N., et al. J. Cell. Sci. 122 (PT 18), 3374-3384 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTNND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of human CTNND2.
NCBI Gene ID #:
1501
NCBI Official Name:
Catenin delta-2
NCBI Official Symbol:
CTNND2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
133 kDa
Protein Accession #:
Q9UQB3
Protein GI Number:
84028193
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9UQB3
User NOte:
Optimal dilutions for each application to be determined by the researcher.