DRAGON Antibody
| Code | Size | Price |
|---|
| PSI-57-567-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Application Note:
For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
Background References:
- Schnichels,S., Gene Expr. Patterns(1), 1-11 (2007)
- Metzger,M., Dev. Dyn. 234 (1), 169-175 (2005)
- Xia,Y., Endocrinology 146 (8), 3614-3621 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB).
NCBI Gene ID #:
285704
NCBI Official Name:
RGM domain family member B
NCBI Official Symbol:
RGMB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q6NW40
Protein GI Number:
327478562
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q6NW40
User NOte:
Optimal dilutions for each application to be determined by the researcher.