DRD2 Antibody
| Code | Size | Price |
|---|
| PSI-58-687-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
D(2) dopamine receptor, Dopamine D2 receptor, DRD2
Application Note:
For WB starting dilution is: 1:2000
Background:
This gene encodes the D2 subtype of the dopamine receptor.
This G-protein coupled receptor inhibits adenylyl cyclase activity.
A missense mutation in this gene causes myoclonus dystonia; other
mutations have been associated with schizophrenia. Alternative
splicing of this gene results in two transcript variants encoding
different isoforms. A third variant has been described, but it has
not been determined whether this form is normal or due to aberrant
splicing.
Background References:
- Verma, V., et al. J. Biol. Chem. 285(45):35092-35103(2010)
- Borroto-Escuela, D.O., et al. Biochem. Biophys. Res. Commun. 401(4):605-610(2010)
- Stelzel, C., et al. J. Neurosci. 30(42):14205-14212(2010)
- Huang, H.Y., et al. J. Formos. Med. Assoc. 109(10):736-739(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.
NCBI Gene ID #:
1813
NCBI Official Name:
D(2) dopamine receptor
NCBI Official Symbol:
DRD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P14416
Protein GI Number:
118206
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P14416
User NOte:
Optimal dilutions for each application to be determined by the researcher.