ABCC9 Antibody
| Code | Size | Price |
|---|
| PSI-59-820-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
superfamily of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and
intra-cellular membranes. ABC genes are divided into seven distinct
subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This
protein is a member of the MRP subfamily which is involved in
multi-drug resistance. This protein is thought to form
ATP-sensitive potassium channels in cardiac, skeletal, and vascular
and non-vascular smooth muscle. Protein structure suggests a role
as the drug-binding channel-modulating subunit of the
extrapancreatic ATP-sensitive potassium channels. No disease has
been associated with this gene thus far. Alternative splicing of
this gene results in several products, two of which result from
differential usage of two terminal exons and one of which results
from exon deletion.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
- Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)
- Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391(1):974-978(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.
NCBI Gene ID #:
10060
NCBI Official Name:
ATP-binding cassette sub-family C member 9
NCBI Official Symbol:
ABCC9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
174 kDa
Protein Accession #:
O60706
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
O60706
User NOte:
Optimal dilutions for each application to be determined by the researcher.