ProSci

HCRTR2 Antibody

Product Code:
 
PSI-58-425
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 3
Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
2 / 3
Western blot analysis in Jurkat cell line lysates (35ug/lane).
3 / 3
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Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in Jurkat cell line lysates (35ug/lane).

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PSI-58-425-400ul400ul£626.00
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Further Information

Additional Names:
Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R, Hypocretin receptor type 2, HCRTR2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
  • Chen, J., et al. Biochem. J. 427(3):377-390(2010)
  • Fellay, J., et al. PLoS Genet.(12), E1000791 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This HCRTR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-304 amino acids from the Central region of human HCRTR2.
NCBI Gene ID #:
3062
NCBI Official Name:
Orexin receptor type 2
NCBI Official Symbol:
HCRTR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
O43614
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
O43614
User NOte:
Optimal dilutions for each application to be determined by the researcher.