TCF7L2 Antibody
| Code | Size | Price |
|---|
| PSI-56-412-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, hTCF-4, TCF7L2, TCF4
Application Note:
For WB starting dilution is: 1:2000
Background:
This gene encodes a high mobility group (HMG)
box-containing transcription factor that plays a key role in the
Wnt signaling pathway. The protein has been implicated in blood
glucose homeostasis. Genetic variants of this gene are associated
with increased risk of type 2 diabetes. Several transcript variants
encoding multiple different isoforms have been found for this gene.
Background References:
- Hansson, O., et al. Curr. Diab. Rep. 10(6):444-451(2010)
- Heni, M., et al. Diabetes (2010) In press :
- Potapov, V.A., et al. Genetika 46(8):1123-1131(2010)
- Kucharska-Newton, A.M., et al.Obes 2010 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TCF7L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human TCF7L2.
NCBI Gene ID #:
6934
NCBI Official Name:
Transcription factor 7-like 2
NCBI Official Symbol:
TCF7L2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q9NQB0
Protein GI Number:
29337146
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NQB0
User NOte:
Optimal dilutions for each application to be determined by the researcher.