SLC25A19 Antibody

ProSci
Product Code: PSI-61-865
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-865-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of SLC25A19 Antibody in mouse cerebellum,heart tissue lysates (35ug/lane)

Western blot analysis of SLC25A19 Antibody in mouse cerebellum,heart tissue lysates (35ug/lane)

Further Information

Additional Names:
Mitochondrial thiamine pyrophosphate carrier, Mitochondrial uncoupling protein 1, Solute carrier family 25 member 19, SLC25A19, DNC, MUP1
Application Note:
For WB starting dilution is: 1:1000
Background:
SLC25A19 encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria.
Background References:
  • Spiegel, R., et al. Ann. Neurol. 66(3):419-424(2009)
  • Kang, J., et al. Mitochondrion 8(2):103-108(2008)
  • Lindhurst, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(43):15927-15932(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This SLC25A19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the C-terminal region of human SLC25A19.
NCBI Gene ID #:
60386
NCBI Official Name:
Mitochondrial thiamine pyrophosphate carrier
NCBI Official Symbol:
SLC25A19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q9HC21
Protein GI Number:
20137652
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9HC21
User NOte:
Optimal dilutions for each application to be determined by the researcher.