B4GALT5 Antibody
| Code | Size | Price |
|---|
| PSI-61-901-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Beta-1,4-galactosyltransferase 5, Beta-1,4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 241-, Beta-1,4-GalT II, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5, B4GALT5
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene is one of seven beta-1,4-galactosyltransferase
(beta4GalT) genes. They encode type II membrane-bound glycoproteins
that appear to have exclusive specificity for the donor substrate
UDP-galactose; all transfer galactose in a beta1,4 linkage to
similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a
distinct function in the biosynthesis of different glycoconjugates
and saccharide structures. As type II membrane proteins, they have
an N-terminal hydrophobic signal sequence that directs the protein
to the Golgi apparatus and which then remains uncleaved to function
as a transmembrane anchor. By sequence similarity, the beta4GalTs
form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and
beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function
of the enzyme encoded by this gene is not clear. This gene was
previously designated as B4GALT4 but was renamed to B4GALT5. In the
literature it is also referred to as beta4GalT2. [provided by
RefSeq].
Background References:
- Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)
- Sato, T., et al. J. Biol. Chem. 282(38):27702-27712(2007)
- Jiang, J., et al. J. Biol. Chem. 281(14):9482-9489(2006)
- Sato, T., et al. J. Biol. Chem. 279(38):39574-39583(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This B4GALT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the C-terminal region of human B4GALT5.
NCBI Gene ID #:
9334
NCBI Official Name:
Beta-1,4-galactosyltransferase 5
NCBI Official Symbol:
B4GALT5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
O43286
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O43286
User NOte:
Optimal dilutions for each application to be determined by the researcher.