OAZ2 Antibody

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ProSci
Product Code: PSI-55-401
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-401-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse lung tissue lysates (35ug/lane).
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OAZ2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in mouse lung tissue lysates (35ug/lane).
OAZ2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2, OAZ2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].
Background References:
  • Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)
  • Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
  • Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005) :
  • Chen, H., et al. J. Biol. Chem. 277(48):45957-45961(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the C-terminal region of human OAZ2.
NCBI Gene ID #:
4947
NCBI Official Name:
Ornithine decarboxylase antizyme 2
NCBI Official Symbol:
OAZ2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
O95190
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O95190
User NOte:
Optimal dilutions for each application to be determined by the researcher.