MMAA Antibody
| Code | Size | Price |
|---|
| PSI-64-120-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Methylmalonic aciduria type A protein, mitochondrial, 36--, MMAA
Application Note:
For WB starting dilution is: 1:500
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.
Background References:
- Honjo, R.S., et al. Genet Test Mol Biomarkers 13(2):181-183(2009)
- Merinero, B., et al. J. Inherit. Metab. Dis. 31(1):55-66(2008)
- Horster, F., et al. Pediatr. Res. 62(2):225-230(2007)
- Padovani, D., et al. J. Biol. Chem. 281(26):17838-17844(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMAA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMAA.
NCBI Gene ID #:
166785
NCBI Official Name:
Methylmalonic aciduria type A protein, mitochondrial
NCBI Official Symbol:
MMAA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q8IVH4
Protein GI Number:
38258173
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8IVH4
User NOte:
Optimal dilutions for each application to be determined by the researcher.