PDPR Antibody

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ProSci
Product Code: PSI-56-175
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-175-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of PDPR Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse testis tissue lysate
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PDPR Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDPR Antibdy for immunohistochemistry.
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Western blot analysis of PDPR Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse testis tissue lysate
PDPR Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDPR Antibdy for immunohistochemistry.

Documents

Further Information

Additional Names:
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial, PDPr, PDPR, KIAA1990
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
PDPR decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity).
Background References:
  • Sugden, M.C., et al. Am. J. Physiol. Endocrinol. Metab. 284 (5), E855-E862 (2003)Ohara, O., et al. DNA Res. 9(2):47-57(2002) Lawson, J.E., et al. J. Biol. Chem. 272(50):31625-31629(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-850 amino acids from the C-terminal region of human PDPR.
NCBI Gene ID #:
55066
NCBI Official Name:
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial
NCBI Official Symbol:
PDPR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
Q8NCN5
Protein GI Number:
182668644
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8NCN5
User NOte:
Optimal dilutions for each application to be determined by the researcher.