MYH9 Antibody
Code | Size | Price |
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PSI-59-654-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Myosin-9, Cellular myosin heavy chain, type A, Myosin heavy chain 9, Myosin heavy chain, non-muscle IIa, Non-muscle myosin heavy chain A, NMMHC-A, Non-muscle myosin heavy chain IIa, NMMHC II-a, NMMHC-IIA, MYH9
Application Note:
For WB starting dilution is: 1:2000
Background:
This gene encodes a myosin IIA heavy chain that contains
an IQ domain and a myosin head-like domain. The protein is involved
in several important functions, including cytokinesis, cell
motility and maintenance of cell shape. Defects in MYH9 are the
cause of non-syndromic sensorineural deafness autosomal dominant
type 17, Epstein syndrome, Alport syndrome with
macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and
macrothrombocytopenia with progressive sensorineural deafness.
Background References:
- Arii, J., et al. Nature 467(7317):859-862(2010)
- Genovese, G., et al. Kidney Int. 78(7):698-704(2010)
- Tzur, S., et al. Hum. Genet. 128(3):345-350(2010)
- Bostrom, M.A., et al. Hum. Genet. 128(2):195-204(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MYH9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1840-1867 amino acids from the C-terminal region of human MYH9.
NCBI Gene ID #:
4627
NCBI Official Name:
Myosin-9
NCBI Official Symbol:
MYH9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
227 kDa
Protein Accession #:
P35579
Protein GI Number:
6166599
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P35579
User NOte:
Optimal dilutions for each application to be determined by the researcher.