RAMP3 Antibody
| Code | Size | Price |
|---|
| PSI-58-214-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the RAMP
family of single-transmembrane-domain proteins, called receptor
(calcitonin) activity modifying proteins (RAMPs). RAMPs are type I
transmembrane proteins with an extracellular N terminus and a
cytoplasmic C terminus. RAMPs are required to transport
calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR, a receptor with seven transmembrane domains, can function as
either a calcitonin-gene-related peptide (CGRP) receptor or an
adrenomedullin receptor, depending on which members of the RAMP
family are expressed. In the presence of this (RAMP3) protein, CRLR
functions as an adrenomedullin receptor.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Bailey, R.J., et al. Peptides 31(4):579-584(2010)
- Harikumar, K.G., et al. Biochemistry 48(49):11773-11785(2009)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human RAMP3.
NCBI Gene ID #:
10268
NCBI Official Name:
Receptor activity-modifying protein 3
NCBI Official Symbol:
RAMP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
O60896
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O60896
User NOte:
Optimal dilutions for each application to be determined by the researcher.