MAP1D Antibody

ProSci
Product Code: PSI-55-466
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-466-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse spleen cell line lysates (35ug/lane).

Western blot analysis in mouse spleen cell line lysates (35ug/lane).

Further Information

Additional Names:
Methionine aminopeptidase 1D, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03174}, MAP 1D {ECO:0000255|HAMAP-Rule:MF_03174}, MetAP 1D {ECO:0000255|HAMAP-Rule:MF_03174}, 341118 {ECO:0000255|HAMAP-Rule:MF_03174}, Methionyl aminopeptidase type 1D, mitochondrial, Peptidase M 1D {ECO:0000255|HAMAP-Rule:MF_03174}, METAP1D, MAP1D
Application Note:
For WB starting dilution is: 1:1000
Background:
The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Leszczyniecka, M., et al. Oncogene 25(24):3471-3478(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAP1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the N-terminal region of human MAP1D.
NCBI Gene ID #:
254042
NCBI Official Name:
Methionine aminopeptidase 1D, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03174}
NCBI Official Symbol:
METAP1D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q6UB28
Protein GI Number:
74710242
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6UB28
User NOte:
Optimal dilutions for each application to be determined by the researcher.