RANBP17 Antibody
| Code | Size | Price |
|---|
| PSI-59-937-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ran-binding protein 17, RANBP17
Application Note:
For WB starting dilution is: 1:1000
Background:
The transport of protein and large RNAs through the
nuclear pore complexes (NPC) is an energy-dependent and regulated
process. The import of proteins with a nuclear localization signal
(NLS) is accomplished by recognition of one or more clusters of
basic amino acids by the importin-alpha/beta complex; see MIM
600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a
key role in NLS-dependent protein import. RAN-binding protein-17 is
a member of the importin-beta superfamily of nuclear transport
receptors.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Kutay, U., et al. J. Biol. Chem. 275(51):40163-40168(2000)
- Koch, P., et al. Biochem. Biophys. Res. Commun. 278(1):241-249(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
NCBI Gene ID #:
64901
NCBI Official Name:
Ran-binding protein 17
NCBI Official Symbol:
RANBP17
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
124 kDa
Protein Accession #:
Q9H2T7
Protein GI Number:
17368945
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9H2T7
User NOte:
Optimal dilutions for each application to be determined by the researcher.