SOSTDC1 Antibody
| Code | Size | Price |
|---|
| PSI-59-173-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Ectodin, Uterine sensitization-associated gene 1 protein, USAG-1, SOSTDC1, USAG1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the sclerostin family and encodes
an N-glycosylated, secreted protein with a C-terminal cystine
knot-like domain. This protein functions as a bone morphogenetic
protein (BMP) antagonist. Specifically, it directly associates with
BMPs, prohibiting them from binding their receptors, thereby
regulating BMP signaling during cellular proliferation,
differentiation, and programmed cell death.
Background References:
- Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
- Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)
- Blish, K.R., et al. Mol. Biol. Cell 19(2):457-464(2008)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SOSTDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the C-terminal region of human SOSTDC1.
NCBI Gene ID #:
25928
NCBI Official Name:
Sclerostin domain-containing protein 1
NCBI Official Symbol:
SOSTDC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q6X4U4
Protein GI Number:
62287504
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6X4U4
User NOte:
Optimal dilutions for each application to be determined by the researcher.