INF2 Antibody

ProSci
Product Code: PSI-59-358
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-358-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in mouse lung tissue lysates (35ug/lane).

Western blot analysis in mouse lung tissue lysates (35ug/lane).

Further Information

Additional Names:
Inverted formin-2, HBEBP2-binding protein C, INF2, C14orf151, C14orf173
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.
Background References:
  • Brown, E.J., et al. Nat. Genet. 42(1):72-76(2010)
  • Chhabra, E.S., et al. J. Biol. Chem. 281(36):26754-26767(2006)
  • Bindschadler, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101(41):14685-14686(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This INF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human INF2.
NCBI Gene ID #:
64423
NCBI Official Name:
Inverted formin-2
NCBI Official Symbol:
INF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
136 kDa
Protein Accession #:
Q27J81
Protein GI Number:
166215588
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q27J81
User NOte:
Optimal dilutions for each application to be determined by the researcher.