Mouse Tgfbr2 Antibody
| Code | Size | Price |
|---|
| PSI-59-113-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, Tgfbr2
Application Note:
For WB starting dilution is: 1:1000
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Background References:
- Droguett, R., et al. Exp. Cell Res. 316(15):2487-2503(2010)
- Robson, A., et al. Dev. Dyn. 239(9):2435-2442(2010)
- Moreno, S.G., et al. Dev. Biol. 342(1):74-84(2010)
- Ouyang, W., et al. Immunity 32(5):642-653(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Tgfbr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of mouse Tgfbr2.
NCBI Gene ID #:
21813
NCBI Official Name:
TGF-beta receptor type-2
NCBI Official Symbol:
Tgfbr2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q62312
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q62312
User NOte:
Optimal dilutions for each application to be determined by the researcher.