ORMDL3 Antibody

ProSci
Product Code: PSI-55-381
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-381-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: mouse testis lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: mouse testis lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
ORM1-like protein 3, ORMDL3
Application Note:
For WB starting dilution is: 1:1000
Background:
Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
Background References:
  • Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010) Liu, X., et al. Nat. Genet. 42(8):658-660(2010) Halapi, E., et al. Eur. J. Hum. Genet. 18(8):902-908(2010) Dobbins, S.E., et al. Int. J. Cancer (2010) In pressMcGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Zebrafish, Xenopus, Bovine
Immunogen:
This ORMDL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human ORMDL3.
NCBI Gene ID #:
94103
NCBI Official Name:
ORM1-like protein 3
NCBI Official Symbol:
ORMDL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
Q8N138
Protein GI Number:
74728486
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8N138
User NOte:
Optimal dilutions for each application to be determined by the researcher.