PTP4A1 Antibody
Code | Size | Price |
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PSI-58-807-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein tyrosine phosphatase type IVA 1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to a small class
of prenylated protein tyrosine phosphatases (PTPs), which contains
a PTP domain and a characteristic C-terminal prenylation motif.
PTPs are cell signaling molecules that play regulatory roles in a
variety of cellular processes. This tyrosine phosphatase is a
nuclear protein, but may primarily associate with plasma membrane.
The surface membrane association of this protein depends on its
C-terminal prenylation. Overexpression of this gene in mammalian
cells conferred a transformed phenotype, which implicated its role
in the tumorigenesis. Studies in rat suggested that this gene may
be an immediate-early gene in mitogen-stimulated cells. [provided
by RefSeq].
Background References:
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
- Skinner, A.L., et al. Biochemistry 48(20):4262-4272(2009)
- Luo, Y., et al. Biochemistry 48(8):1838-1846(2009)
- Min, S.H., et al. Oncogene 28(4):545-554(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
NCBI Gene ID #:
7803
NCBI Official Name:
Protein tyrosine phosphatase type IVA 1
NCBI Official Symbol:
PTP4A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q93096
Protein GI Number:
68566217
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q93096
User NOte:
Optimal dilutions for each application to be determined by the researcher.