PTP gamma Antibody
| Code | Size | Price |
|---|
| PSI-63-461-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
Application Note:
For WB starting dilution is: 1:1000
Background:
PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Background References:
- Liu, S., et al., Breast Cancer Res. Treat. 71(1):21-35 (2002).
- Kastury, K., et al., Genomics 32(2):225-235 (1996).
- Barnea, G., et al., Mol. Cell. Biol. 13(3):1497-1506 (1993).
- LaForgia, S., et al., Proc. Natl. Acad. Sci. U.S.A. 88(11):5036-5040 (1991).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTP gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-782 amino acids from the Central region of human PTP gamma.
NCBI Gene ID #:
5793
NCBI Official Name:
Receptor-type tyrosine-protein phosphatase gamma
NCBI Official Symbol:
PTPRG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
162 kDa
Protein Accession #:
P23470
Protein GI Number:
229463033
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
P23470
User NOte:
Optimal dilutions for each application to be determined by the researcher.