Mouse Map4k4 Antibody

ProSci
Product Code: PSI-57-749
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-749-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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Western blot analysis in mouse brain tissue lysates (35ug/lane).

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Western blot analysis in mouse brain tissue lysates (35ug/lane).

Further Information

Additional Names:
Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase, Map4k4, Nik
Application Note:
For WB starting dilution is: 1:1000
Background:
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway.
Background References:
  • Maruyama, T., et al. J. Bone Miner. Res. 25(5):1058-1067(2010)
  • Guntur, K.V., et al. J. Biol. Chem. 285(9):6595-6603(2010)
  • Aouadi, M., et al. Nature 458(7242):1180-1184(2009)
  • Wittwer, T., et al. Biochem. Biophys. Res. Commun. 371(2):294-297(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Map4k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the Central region of mouse Map4k4.
NCBI Gene ID #:
26921
NCBI Official Name:
Mitogen-activated protein kinase kinase kinase kinase 4
NCBI Official Symbol:
Map4k4
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
141 kDa
Protein Accession #:
P97820
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P97820
User NOte:
Optimal dilutions for each application to be determined by the researcher.