TNNT2 Antibody
| Code | Size | Price |
|---|
| PSI-58-582-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is the
tropomyosin-binding subunit of the troponin complex, which is
located on the thin filament of striated muscles and regulates
muscle contraction in response to alterations in intracellular
calcium ion concentration. Mutations in this gene have been
associated with familial hypertrophic cardiomyopathy as well as
with dilated cardiomyopathy. Transcripts for this gene undergo
alternative splicing that results in many tissue-specific isoforms,
however, the full-length nature of some of these variants has not
yet been determined.
Background References:
- Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Millat, G., et al. EurMed Genet 53(5):261-267(2010)
- Watt, K.D., et al. Liver Transpl. 16(8):990-998(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rb
Immunogen:
This TNNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the Central region of human TNNT2.
NCBI Gene ID #:
7139
NCBI Official Name:
Troponin T, cardiac muscle
NCBI Official Symbol:
TNNT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
P45379
Protein GI Number:
21264536
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P45379
User NOte:
Optimal dilutions for each application to be determined by the researcher.