MAP3K11 Antibody
| Code | Size | Price |
|---|
| PSI-61-820-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11 (HGNC:6850)
Application Note:
For WB starting dilution is: 1:1000
Background:
MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Background References:
- Rangasamy, V., et al. Cancer Res. 70(4):1731-1740(2010)
- Velho, S., et al. Hum. Mol. Genet. 19(4):697-706(2010)
- Cole, E.T., et al. Biochim. Biophys. Acta 1793(12):1811-1818(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAP3K11 antibody is generated from rabbits immunized with MAP3K11 recombinant protein.
NCBI Gene ID #:
4296
NCBI Official Name:
Mitogen-activated protein kinase kinase kinase 11
NCBI Official Symbol:
MAP3K11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
Q16584
Protein GI Number:
71153819
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q16584
User NOte:
Optimal dilutions for each application to be determined by the researcher.