LRRC16A Antibody
| Code | Size | Price |
|---|
| PSI-59-733-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Leucine-rich repeat-containing protein 16A, CARMIL homolog, LRRC16A, CARMIL, CARMIL1a, LRRC16
Application Note:
For WB starting dilution is: 1:1000
Background:
LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Polasek, O., et al. Croat. Med. J. 51(1):32-39(2010)
- Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010)
- van der Harst, P., et al. Hum. Mol. Genet. 19(2):387-395(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1178 amino acids from the C-terminal region of human LRRC16A.
NCBI Gene ID #:
55604
NCBI Official Name:
Leucine-rich repeat-containing protein 16A
NCBI Official Symbol:
LRRC16A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
152 kDa
Protein Accession #:
Q5VZK9
Protein GI Number:
74762279
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q5VZK9
User NOte:
Optimal dilutions for each application to be determined by the researcher.