CDC42EP2 Antibody
| Code | Size | Price |
|---|
| PSI-58-973-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
Application Note:
For WB starting dilution is: 1:1000
Background:
CDC42, a small Rho GTPase, regulates the formation of
F-actin-containing structures through its interaction with the
downstream effector proteins. The protein encoded by this gene is a
member of the Borg family of CDC42 effector proteins. Borg family
proteins contain a CRIB (Cdc42/Rac interactive-binding) domain.
They bind to, and negatively regulate the function of, CDC42.
Coexpression of this protein with dominant negative mutant CDC42
protein in fibroblast was found to induce pseudopodia formation,
which suggested a role of this protein in actin filament assembly
and cell shape control.
Background References:
- Xue, Y., et al. Int. J. Cancer 118(12):2965-2972(2006)
- Joberty, G., et al. Nat. Cell Biol. 3(10):861-866(2001)
- Hirsch, D.S., et al. J. Biol. Chem. 276(2):875-883(2001)
- Joberty, G., et al. Mol. Cell. Biol. 19(10):6585-6597(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2.
NCBI Gene ID #:
10435
NCBI Official Name:
Cdc42 effector protein 2
NCBI Official Symbol:
CDC42EP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O14613
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14613
User NOte:
Optimal dilutions for each application to be determined by the researcher.