Tnks 2 Antibody

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ProSci
Product Code: PSI-61-877
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-877-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the detected Tnks 2 protein (arrow).
2 / 2
Flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the detected Tnks 2 protein (arrow).
Flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Documents

Further Information

Additional Names:
Tankyrase-2, TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, TNKS2, PARP5B, TANK2, TNKL
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.
Background References:
  • Varadi, V., et al. Eur. J. Cancer 45(17):3008-3016(2009)
  • Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57(6):871-881(2008)
  • Sidorova, N.N., et al. Biochemistry Mosc. 73(3):289-295(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1126-1156 amino acids from the C-terminal region of human Tnks 2.
NCBI Gene ID #:
80351
NCBI Official Name:
Tankyrase-2
NCBI Official Symbol:
TNKS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
127 kDa
Protein Accession #:
Q9H2K2
Protein GI Number:
20140805
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q9H2K2
User NOte:
Optimal dilutions for each application to be determined by the researcher.