ITGA1 Antibody

ProSci
Product Code: PSI-63-654
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-654-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of ITGA1 Antibody in mouse cerebellum tissue lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human brain tissue reacted with ITGA1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis of ITGA1 Antibody in mouse cerebellum tissue lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human brain tissue reacted with ITGA1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD49a, ITGA1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Background References:
  • Bank,I., et.al., J. Clin. Immunol. 11 (1), 29-38 (1991)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1.
NCBI Gene ID #:
3672
NCBI Official Name:
Integrin alpha-1
NCBI Official Symbol:
ITGA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
131 kDa
Protein Accession #:
P56199
Protein GI Number:
124056463
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P56199
User NOte:
Optimal dilutions for each application to be determined by the researcher.