PP1R14C Antibody
| Code | Size | Price |
|---|
| PSI-55-061-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The degree of protein phosphorylation is regulated by a
balance of protein kinase and phosphatase activities. Protein
phosphatase-1 (PP1; see MIM 176875) is a signal-transducing
phosphatase that influences neuronal activity, protein synthesis,
metabolism, muscle contraction, and cell division. PPP1R14C is an
inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by
OMIM].
Background References:
- Daskalow, K., et al. Anticancer Res. 30(5):1573-1578(2010)
- Scholz, S.W., et al. Ann. Neurol. 65(5):610-614(2009)
- Burgner, D., et al. PLoS Genet.(1), E1000319 (2009) :
- Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PP1R14C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the C-terminal region of human PP1R14C.
NCBI Gene ID #:
81706
NCBI Official Name:
Protein phosphatase 1 regulatory subunit 14C
NCBI Official Symbol:
PPP1R14C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
Q8TAE6
Protein GI Number:
90110047
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8TAE6
User NOte:
Optimal dilutions for each application to be determined by the researcher.