FYTD1 Antibody

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ProSci
Product Code: PSI-61-841
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-841-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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(LEFT)Western blot analysis of FYTD1 Antibody in A375 cell line lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.(RIGHT)Western blot analysis of FYTD1 Antibody in mouse liver tissue lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.
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FYTD1 Antibody IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
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(LEFT)Western blot analysis of FYTD1 Antibody in A375 cell line lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.(RIGHT)Western blot analysis of FYTD1 Antibody in mouse liver tissue lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.
FYTD1 Antibody IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
UAP56-interacting factor, Forty-two-three domain-containing protein 1, Protein 40-2-3, FYTTD1, UIF
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
FYTD1 required for mRNA export from the nucleus to the cytoplasm. This protein acts as an adapter that uses the BAT1/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. FYTD1 associates with spliced and unspliced mRNAs simultaneously with THOC4.
Background References:
  • Hautbergue, G.M., et al. Curr. Biol. 19(22):1918-1924(2009)
  • Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This FYTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human FYTD1.
NCBI Gene ID #:
84248
NCBI Official Name:
UAP56-interacting factor
NCBI Official Symbol:
FYTTD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q96QD9
Protein GI Number:
284018159
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96QD9
User NOte:
Optimal dilutions for each application to be determined by the researcher.