GCC2 Antibody

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ProSci
Product Code: PSI-55-082
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-082-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the detected GCC2 protein (arrow).
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GCC2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the detected GCC2 protein (arrow).
GCC2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
GRIP and coiled-coil domain-containing protein 2, 185 kDa Golgi coiled-coil protein, GCC185, CLL-associated antigen KW-11, CTCL tumor antigen se1-1, Ran-binding protein 2-like 4, RanBP2L4, Renal carcinoma antigen NY-REN-53, GCC2, KIAA0336, RANBP2L4
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants.
Background References:
  • Houghton, F.J., et al. Cell 138(4):787-794(2009)
  • Hayes, G.L., et al. Mol. Biol. Cell 20(1):209-217(2009)
  • Burguete, A.S., et al. Cell 132(2):286-298(2008)
  • Efimov, A., et al. Dev. Cell 12(6):917-930(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This GCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1581-1609 amino acids from the C-terminal region of human GCC2.
NCBI Gene ID #:
9648
NCBI Official Name:
GRIP and coiled-coil domain-containing protein 2
NCBI Official Symbol:
GCC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
196 kDa
Protein Accession #:
Q8IWJ2
Protein GI Number:
313104307
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8IWJ2
User NOte:
Optimal dilutions for each application to be determined by the researcher.