Stanniocalcin-2 Antibody

Contact us
ProSci
Product Code: PSI-57-734
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-734-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis of anti-STC2 Antibody in mouse kidney tissue lysates (35ug/lane). STC2 was detected using the purified polyclonal antibody.
2 / 2
Stanniocalcin-2 (STC2) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Stanniocalcin-2 (STC2) Antibody for immunohistochemistry.
❮❯

Western blot analysis of anti-STC2 Antibody in mouse kidney tissue lysates (35ug/lane). STC2 was detected using the purified polyclonal antibody.
Stanniocalcin-2 (STC2) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Stanniocalcin-2 (STC2) Antibody for immunohistochemistry.

Documents

Further Information

Additional Names:
Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.
Background References:
  • Ishibashi, K., et al., Biochem. Biophys. Res. Commun. 250(2):252-258 (1998).
  • DiMattia, G.E., et al., Mol. Cell. Endocrinol. 146 (1-2), 137-140 (1998).
  • Chang, A.C., et al., Mol. Cell. Endocrinol. 141 (1-2), 95-99 (1998).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Stanniocalcin-2 (STC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human Stanniocalcin-2 (STC2).
NCBI Gene ID #:
8614
NCBI Official Name:
Stanniocalcin-2
NCBI Official Symbol:
STC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
O76061
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
O76061
User NOte:
Optimal dilutions for each application to be determined by the researcher.