PFDN5 Antibody

ProSci
Product Code: PSI-56-862
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-862-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).
2 / 3
Western blot analysis in mouse heart tissue lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

Further Information

Additional Names:
Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].
Background References:
  • Ma, H.C., et al. J. Biomed. Sci. 15(4):417-425(2008)
  • Yoshida, T., et al. Exp. Cell Res. 314(6):1217-1228(2008)
  • Lubyova, B., et al. J. Biol. Chem. 282(44):31944-31953(2007)
  • Hagio, Y., et al. J. Cell. Biochem. 97(1):145-155(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PFDN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human PFDN5.
NCBI Gene ID #:
5204
NCBI Official Name:
Prefoldin subunit 5
NCBI Official Symbol:
PFDN5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
Q99471
Protein GI Number:
12231038
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q99471
User NOte:
Optimal dilutions for each application to be determined by the researcher.