PFDN5 Antibody
Code | Size | Price |
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PSI-56-862-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the prefoldin alpha subunit
family. The encoded protein is one of six subunits of prefoldin, a
molecular chaperone complex that binds and stabilizes newly
synthesized polypeptides, thereby allowing them to fold correctly.
The complex, consisting of two alpha and four beta subunits, forms
a double beta barrel assembly with six protruding coiled-coils. The
encoded protein may also repress the transcriptional activity of
the proto-oncogene c-Myc. Alternatively spliced transcript variants
encoding different isoforms have been described. [provided by
RefSeq].
Background References:
- Ma, H.C., et al. J. Biomed. Sci. 15(4):417-425(2008)
- Yoshida, T., et al. Exp. Cell Res. 314(6):1217-1228(2008)
- Lubyova, B., et al. J. Biol. Chem. 282(44):31944-31953(2007)
- Hagio, Y., et al. J. Cell. Biochem. 97(1):145-155(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PFDN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human PFDN5.
NCBI Gene ID #:
5204
NCBI Official Name:
Prefoldin subunit 5
NCBI Official Symbol:
PFDN5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
Q99471
Protein GI Number:
12231038
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q99471
User NOte:
Optimal dilutions for each application to be determined by the researcher.