CDKL1 Antibody

ProSci
Product Code: PSI-62-966
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-966-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.
2 / 4
Antibody is used in Western blot to detect CDKL1 in mouse kidney tissue lysate.
3 / 4
4 / 4
Western blot analysis in 293 cell line lysates (35ug/lane).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.
Antibody is used in Western blot to detect CDKL1 in mouse kidney tissue lysate.
Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
Cyclin-dependent kinase-like 1, Protein kinase p42 KKIALRE, Serine/threonine-protein kinase KKIALRE, CDKL1
Application Note:
For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000
Background:
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Alternative splice variants encoding different protein isoforms have been described, but their full-length nature has not been determined.
Background References:
  • Meyerson, M., et al., EMBO J. 11(8):2909-2917 (1992).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-316 amino acids from the C-terminal region of human CDKL1.
NCBI Gene ID #:
8814
NCBI Official Name:
Cyclin-dependent kinase-like 1
NCBI Official Symbol:
CDKL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q00532
Protein GI Number:
229463050
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q00532
User NOte:
Optimal dilutions for each application to be determined by the researcher.