LTBP1 Antibody

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ProSci
Product Code: PSI-63-200
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-63-200-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
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Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Latent-transforming growth factor beta-binding protein 1, LTBP-1, Transforming growth factor beta-1-binding protein 1, TGF-beta1-BP-1, LTBP1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
LTBP1 may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. This protein may play critical roles in controlling and directing the activity of TGFB1, and it may have a structural role in the extra cellular matrix (ECM).
Background References:
  • Olofsson A., J. Biol. Chem. 270:31294-31297(1995)
  • Kanzaki T., Cell 61:1051-1061(1990)
  • Isogai Z., J. Biol. Chem. 278:2750-2757(2003)
  • Oklu R., Biochem. J. 352:601-610(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1493-1525 amino acids from the C-terminal region of human LTBP1.
NCBI Gene ID #:
4052
NCBI Official Name:
Latent-transforming growth factor beta-binding protein 1
NCBI Official Symbol:
LTBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
187 kDa
Protein Accession #:
Q14766
Protein GI Number:
290457687
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q14766
User NOte:
Optimal dilutions for each application to be determined by the researcher.