CRABP1 Antibody

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ProSci
Product Code: PSI-61-922
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-922-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + MOLT-4 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
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Western Blot at 1:1000 dilution + MOLT-4 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I, CRABP1, RBP5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
Background References:
  • Tang, X.H., et al. Exp. Cell Res. 314(1):38-51(2008)
  • Uhrig, M., et al. BMC Med 6, 38 (2008) :
  • Guidez, F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(47):18694-18699(2007)
  • Tanaka, K., et al. Oncogene 26(44):6456-6468(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
Immunogen:
This CRABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human CRABP1.
NCBI Gene ID #:
1381
NCBI Official Name:
Cellular retinoic acid-binding protein 1
NCBI Official Symbol:
CRABP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
P29762
Protein GI Number:
266904
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P29762
User NOte:
Optimal dilutions for each application to be determined by the researcher.