MYOZ1 Antibody

ProSci
Product Code: PSI-61-856
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-856-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of MYOZ1 Antibody in MDA-MB231 cell line lysates (35ug/lane)
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MYOZ1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of MYOZ1 Antibody in MDA-MB231 cell line lysates (35ug/lane)
MYOZ1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Myozenin-1, Calsarcin-2, Filamin-, actinin- and telethonin-binding protein, Protein FATZ, MYOZ1 (HGNC:13752)
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. This protein plays an important role in the modulation of calcineurin signaling, may play a role in myofibrillogenesis.
Background References:
  • Aurino, S., et al. Acta Myol 27, 90-97 (2008) Posch, M.G., et al. Mol. Genet. Metab. 91(2):207-208(2007) Arola, A.M., et al. Mol. Genet. Metab. 90(4):435-440(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This MYOZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the Central region of human MYOZ1.
NCBI Gene ID #:
58529
NCBI Official Name:
Myozenin-1
NCBI Official Symbol:
MYOZ1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q9NP98
Protein GI Number:
74734300
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NP98
User NOte:
Optimal dilutions for each application to be determined by the researcher.