LPAR6 Antibody

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ProSci
Product Code: PSI-56-596
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-596-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse heart tissue lysates (35ug/lane).
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LPAR6 Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LPAR6 Antibdy for immunohistochemistry.
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Western blot analysis in mouse heart tissue lysates (35ug/lane).
LPAR6 Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LPAR6 Antibdy for immunohistochemistry.

Documents

Further Information

Additional Names:
Lysophosphatidic acid receptor 6, LPA receptor 6, LPA-6, Oleoyl-L-alpha-lysophosphatidic acid receptor, P2Y purinoceptor 5, P2Y5, Purinergic receptor 5, RB intron encoded G-protein coupled receptor, LPAR6, P2RY5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants.
Background References:
  • Pasternack, S.M., et al. Arch. Dermatol. Res. 301(8):621-624(2009)
  • Yanagida, K., et al. J. Biol. Chem. 284(26):17731-17741(2009)
  • Tariq, M., et al. Br. J. Dermatol. 160(5):1006-1010(2009)
  • Shimomura, Y., et al. J. Invest. Dermatol. 129(3):622-628(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This LPAR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human LPAR6.
NCBI Gene ID #:
10161
NCBI Official Name:
Lysophosphatidic acid receptor 6
NCBI Official Symbol:
LPAR6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P43657
Protein GI Number:
34223726
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
P43657
User NOte:
Optimal dilutions for each application to be determined by the researcher.