CBX2 Antibody
| Code | Size | Price |
|---|
| PSI-58-983-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Chromobox protein homolog 2, CBX2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a component of the polycomb multiprotein
complex, which is required to maintain the transcriptionally
repressive state of many genes throughout development via chromatin
remodeling and modification of histones. Disruption of this gene in
mice results in male-to-female gonadal sex reversal. Mutations in
this gene are also associated with gonadal dysgenesis in humans.
Alternatively spliced transcript variants encoding different
isoforms have been noted for this gene.
Background References:
- Biason-Lauber, A., et al. Am. J. Hum. Genet. 84(5):658-663(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Agrawal, N., et al. PLoS ONE(12), E4032 (2008) :
- Garcia, E., et al. EMBO J. 18(12):3404-3418(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of human CBX2.
NCBI Gene ID #:
84733
NCBI Official Name:
Chromobox protein homolog 2
NCBI Official Symbol:
CBX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q14781
Protein GI Number:
77416853
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14781
User NOte:
Optimal dilutions for each application to be determined by the researcher.