KLHL12 Antibody
| Code | Size | Price |
|---|
| PSI-59-118-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Kelch-like protein 12, CUL3-interacting protein 1, DKIR homolog, hDKIR, KLHL12, C3IP1
Application Note:
For WB starting dilution is: 1:1000
Background:
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Background References:
- Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
- Rondou, P., et al. J. Biol. Chem. 283(17):11083-11096(2008)
- Lim, J., et al. Cell 125(4):801-814(2006)
- Angers, S., et al. Nat. Cell Biol. 8(4):348-357(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Rat, Xenopus
Immunogen:
This KLHL12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12.
NCBI Gene ID #:
59349
NCBI Official Name:
Kelch-like protein 12
NCBI Official Symbol:
KLHL12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q53G59
Protein GI Number:
97054498
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q53G59
User NOte:
Optimal dilutions for each application to be determined by the researcher.