HEXIM2 Antibody

ProSci
Product Code: PSI-61-257
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-257-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:8000 dilution Lane 1: mouse testis lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:8000 dilution Lane 1: mouse testis lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2, HEXIM2
Application Note:
For WB starting dilution is: 1:8000
Background:
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Background References:
  • Petroziello J.,et al.Oncogene 23:7734-7745(2004).
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
  • Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
  • Byers S.A.,et al.J. Biol. Chem. 280:16360-16367(2005).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HEXIM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-269 amino acids from of human HEXIM2.
NCBI Gene ID #:
124790
NCBI Official Name:
Protein HEXIM2
NCBI Official Symbol:
HEXIM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q96MH2
Protein GI Number:
74732374
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96MH2
User NOte:
Optimal dilutions for each application to be determined by the researcher.