GTF2B Antibody
| Code | Size | Price |
|---|
| PSI-57-669-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B, TF2B, TFIIB
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the general transcription factor IIB,
one of the ubiquitous factors required for transcription initiation
by RNA polymerase II. The protein localizes to the nucleus where it
forms a complex (the DAB complex) with transcription factors IID
and IIA. Transcription factor IIB serves as a bridge between IID,
the factor which initially recognizes the promoter sequence, and
RNA polymerase II.
Background References:
- Wang, Y., et al. Curr. Biol. 20(6):548-553(2010)
- Thompson, N.E., et al. J. Biol. Chem. 284(37):24754-24766(2009)
- Gilman, B., et al. J. Biol. Chem. 284(14):9093-9098(2009)
- Vogt, C., et al. J. Virol. 82(22):11446-11453(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Immunogen:
This GTF2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human GTF2B.
NCBI Gene ID #:
2959
NCBI Official Name:
Transcription initiation factor IIB
NCBI Official Symbol:
GTF2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q00403
Protein GI Number:
135629
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q00403
User NOte:
Optimal dilutions for each application to be determined by the researcher.