Ribophorin Antibody
| Code | Size | Price |
|---|
| PSI-61-382-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1, RPN1
Application Note:
For WB starting dilution is: 1:1000
Background:
Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasic reticulum, that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein. RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1. The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.
Background References:
- Fu, J., et al., J. Biol. Chem. 275(6):3984-3990 (2000). Pekarsky, Y., et al., Cancer Res. 57(18):3914-3919 (1997). Crimaudo, C., et al., EMBO J. 6(1):75-82 (1987).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This Ribophorin (RPN1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-561 amino acids from the C-terminal region of human Ribophorin (RPN1).
NCBI Gene ID #:
6184
NCBI Official Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
NCBI Official Symbol:
RPN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
P04843
Protein GI Number:
132559
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P04843
User NOte:
Optimal dilutions for each application to be determined by the researcher.