NUBPL Antibody
| Code | Size | Price |
|---|
| PSI-59-620-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Iron-sulfur protein NUBPL, IND1 homolog, Nucleotide-binding protein-like, huInd1, NUBPL, C14orf127
Application Note:
For WB starting dilution is: 1:1000
Background:
Respiratory complex I (NADH:ubiquinone oxidoreductase EC
1.6.5.3) is a large mitochondrial inner membrane enzyme consisting
of 45 subunits and 8 iron-sulfur (Fe/S) clusters. NUBPL, or IND1,
is an Fe/ S protein that plays a critical role in the assembly of
respiratory complex I, likely by transferring Fe/S into the
Fe/S-containing complex I subunits (Sheftel et al., 2009 [PubMed
19752196]).
Background References:
- Calvo, S.E., et al. Nat. Genet. 42(10):851-858(2010)
- Sheftel, A.D., et al. Mol. Cell. Biol. 29(22):6059-6073(2009)
- Volpi, S., et al. Mol. Psychiatry 14(11):1024-1031(2009)
- Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-67 amino acids from the N-terminal region of human NUBPL.
NCBI Gene ID #:
80224
NCBI Official Name:
Iron-sulfur protein NUBPL
NCBI Official Symbol:
NUBPL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q8TB37
Protein GI Number:
116242683
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TB37
User NOte:
Optimal dilutions for each application to be determined by the researcher.