MRPL24 Antibody
Code | Size | Price |
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PSI-60-527-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24, MRPL24
Application Note:
For WB starting dilution is: 1:1000
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL24 is a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24).
Background References:
- Zhang, Z., et al., Genomics 81(5):468-480 (2003).
- O'Brien, T.W., et al., J. Biol. Chem. 275(24):18153-18159 (2000).
- Kenmochi, N., et al., Genomics 77 (1-2), 65-70 (2001).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRPL24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-214 amino acids from the C-terminal region of human MRPL24.
NCBI Gene ID #:
79590
NCBI Official Name:
39S ribosomal protein L24, mitochondrial
NCBI Official Symbol:
MRPL24
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q96A35
Protein GI Number:
74751733
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
Q96A35
User NOte:
Optimal dilutions for each application to be determined by the researcher.