CRYBA4 Antibody
| Code | Size | Price |
|---|
| PSI-58-785-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Beta-crystallin A4, Beta-A4 crystallin, CRYBA4
Application Note:
For WB starting dilution is: 1:1000
Background:
Crystallins are separated into two classes:
taxon-specific, or enzyme, and ubiquitous. The latter class
constitutes the major proteins of vertebrate eye lens and maintains
the transparency and refractive index of the lens. Since lens
central fiber cells lose their nuclei during development, these
crystallins are made and then retained throughout life, making them
extremely stable proteins. Mammalian lens crystallins are divided
into alpha, beta, and gamma families; beta and gamma crystallins
are also considered as a superfamily. Alpha and beta families are
further divided into acidic and basic groups. Seven protein regions
exist in crystallins: four homologous motifs, a connecting peptide,
and N- and C-terminal extensions. Beta-crystallins, the most
heterogeneous, differ by the presence of the C-terminal extension
(present in the basic group, none in the acidic group).
Beta-crystallins form aggregates of different sizes and are able to
self-associate to form dimers or to form heterodimers with other
beta-crystallins. This gene, a beta acidic group member, is part of
a gene cluster with beta-B1, beta-B2, and beta-B3. [provided by
RefSeq].
Background References:
- Zhou, G., et al. Mol. Vis. 16, 1019-1024 (2010) :
- Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009) :
- Billingsley, G., et al. Am. J. Hum. Genet. 79(4):702-709(2006)
- Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CRYBA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the C-terminal region of human CRYBA4.
NCBI Gene ID #:
1413
NCBI Official Name:
Beta-crystallin A4
NCBI Official Symbol:
CRYBA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
P53673
Protein GI Number:
2506318
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P53673
User NOte:
Optimal dilutions for each application to be determined by the researcher.