MUTYH Antibody
| Code | Size | Price |
|---|
| PSI-63-813-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Background References:
- Kim C.J., et.al., Oncogene 23:6820-6822(2004).
- Isidro G., et.al., Hum. Mutat. 24:353-354(2004).
- Sieber O.M., et.al., N. Engl. J. Med. 348:791-799(2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.
NCBI Gene ID #:
4595
NCBI Official Name:
A/G-specific adenine DNA glycosylase
NCBI Official Symbol:
MUTYH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q9UIF7
Protein GI Number:
48428272
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
Q9UIF7
User NOte:
Optimal dilutions for each application to be determined by the researcher.