DCLRE1C Antibody

ProSci
Product Code: PSI-64-086
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-086-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: HT-29 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: mouse heart lysate Lane 5: MCF-7 whole cell lysate Lane 5: PC-3 whole cell lysate Lane 5: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.
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DCLRE1C Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western Blot at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: HT-29 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: mouse heart lysate Lane 5: MCF-7 whole cell lysate Lane 5: PC-3 whole cell lysate Lane 5: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.
DCLRE1C Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Protein artemis, 31--, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein, DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C
Application Note:
For WB starting dilution is: 1:2000

For IHC-P starting dilution is: 1:50~100
Background:
DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.
Background References:
  • Beucher, A., et al. EMBO J. 28(21):3413-3427(2009)
  • Rivera-Munoz, P., et al. Blood 114(17):3601-3609(2009)
  • Wang, H., et al. J. Biol. Chem. 284(27):18236-18243(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DCLRE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human DCLRE1C.
NCBI Gene ID #:
64421
NCBI Official Name:
Protein artemis
NCBI Official Symbol:
DCLRE1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
Q96SD1
Protein GI Number:
71153325
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96SD1
User NOte:
Optimal dilutions for each application to be determined by the researcher.